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Vitamin B12 is essential for red blood cell production, nerve function, and DNA synthesis

Dosing appears to play a role some trials have shown antioxidant effects with 800mg/day, while others suggest stronger responses at 1,2002,400mg/day, particularly for lowering oxidative stress biomarkers in patients with multiple sclerosis.3 28 Keep in mind, though: while higher doses (typically 1,2002,400mg per day) may offer stronger antioxidant effects, they also come with a greater chance of side effects like upset stomach or dizziness

In vivo, improved cartilage repair was achieved by articular injection of MSCs with high levels of cellular GSH and MSCs cultured under high-density conditions, as confirmed by Collagen type 2 IHC, Safranin-O staining and ODriscoll scores showing that more hyaline cartilage was formed on the defects

[DOI] [PubMed] [Google Scholar] 20.Zhao F., Zhang J., Chang N
