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However, the co-expression of all four Rspondins predominantly in the DP is likely to complicate the analysis of a single ablation as a result of functional redundancy or accumulative effects that are proportional to the levels of each Rspondin

doi: 10.1186/s12986-017-0200-8

As an important component of pain processing, targeting interleukin-6 could be a promising lead to novel therapeutic strategies for pathological pain (Zhou et al., 2016a)
The CC-type GRXs are only found in higher plants
