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10.1161/CIRCRESAHA.117.303776 168 LandmesserU.DikalovS.PriceS

[DOI] [PubMed] [Google Scholar] 60.Shan Y., Akram A., Amatullah H., Zhou D.Y., Gali P.L., Maron-Gutierrez T., Gonzalez-Lopez A., Zhou L., Rocco P.R., Hwang D., et al
Lipid peroxidation is central to membrane disruption: oxidation of polyunsaturated fatty acids (e.g., arachidonic acid, docosahexaenoic acid) generates lipid peroxides (e.g., 4-HNE), which crosslink with amino groups of membrane phospholipids, destabilizing the lipid bilayer and increasing permeability
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