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10.1007/s00204-014-1312-9 91
63 Hypothalamic sensing of fluctuations in circulatory lipid levels triggers efferent vagus nerve-mediated output that regulates hepatic glucose production and glucose homeostasis
It modulates inflammatory cytokines and supports the gut-brain-immune axis, making it effective for both musculoskeletal injuries and gastrointestinal disorders
However, high-dose niacin (as a medication for cholesterol) is generally not recommended during breastfeeding, because significant amounts could enter milk and cause unwanted effects in the nursing infant (flushing, for example)
