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The mitochondria become sluggish, fragmented, and unable to meet the daily energy demands of the body, resulting in the debilitating, leaden fatigue that characterizes these conditions

doi: 10.1080/10408398.2019.1657063

RER was significantly lower at baseline during the L-carnitine condition when compared to the placebo condition

Measurements of the concentrations of carnitine, acetylcarnitine, and microbiotaderived metabolites can provide an estimate of the time and concentrationdependent microbial metabolism of these substances