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Notably, carboplatin combined with PHGDH inhibition significantly suppressed Np63-mediated tumor growth, indicating that inhibition of serine synthesis can counteract Np63-mediated carboplatin resistance

PMID 31451866

ICS are anti-inflammatory agents currently recommended for use with long-acting bronchodilators to prevent exacerbations in patients with moderate-to-severe COPD, especially those with eosinophilic airway inflammation

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