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The inter-individual toxicokinetic and interspecies uncertainty factors were waived on the premise that the in vitro model was derived from human lung biopsies, the readouts measure MIEs for the mode of action (direct acting contact irritation) and the exposure modelling is sufficiently realistic and accurate

For this reason, experts advocate using only supervised clinical settings with greater regulation as a means of protecting patients

Malonaldehyde formation and DNA fragmentation: two independent sperm decays linked to reactive oxygen species

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