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Principles of early drug discovery
These results clearly indicate that the presence of ortho-substituted phenolic hydroxyl groups is very important for the stable binding of these scaffolds with NFB
doi: 10.4155/bio-2016-0289 210 GrandeaAGOlsenOACoxTCRenshawMHammondPWChan-HuiPYet al
Even large intranuclear vacuoles are mostly undetectable with optical magnifications used in conventional ICSI but they do appear at the magnification used in IMSI (Figure 2B) so that injection of spermatozoa with such vacuoles into oocytes can be avoided [191,193]
