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There was no marked association between DUSP1/MKP-1 expression levels and OS (P=0.058)
doi: 10.4088/JCP.15r09984
However, clinical responses vary, and not all patients demonstrate sustained benefit across all symptom domains 2,9,14,1721 , leading to uncertainty in treatment decisions and hesitancy in offering surgical intervention given its associated risks and healthcare burden
Olszewska-Pazdrak B, Hart-Vantassell A, Carney DH (2010) Thrombin peptide TP508 stimulates rapid nitric oxide production in human endothelial cells
