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Mechanisms and therapeutics of n-acetylcysteine: a recent update
Cr Biol 337(1):2943
Depleted GSH directly limits detox capacity, creating a bottleneck that no other intervention can compensate for

Third, molecular pathways underlying antioxidant enzyme regulation and iNOS inhibition were inferred based on biochemical and histological outcomes rather than confirmed through gene or protein-level signaling assays