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Hering J, Garrean S, Dekoj TR et al (2007) Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells

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The IDO inhibitor, 1-methyl-tryptophan, increased Mtb killing and resulted in the reorganization of the macaque granuloma architecture enabling the trafficking of lymphocytes into the lesion core enabling increased T cell proliferation with increased frequency of granzyme-expressing T cells potentially controlling lung tissue events ( L -isoleucine in mice significantly increased beta-defensins which was associated with reduced lung mycobacterial burden of multi-drug resistant Mtb strains and decreased pulmonary pathology ( Lactate Metabolism Lactate dehydrogenase A (LDHA) catalyzes pyruvate into L-lactate during glycolysis

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