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Abstract Progesterone-receptor membrane component 1 (PGRMC1/Sigma-2 receptor) is a haem-containing protein that interacts with epidermal growth factor receptor (EGFR) and cytochromes P450 to regulate cancer proliferation and chemoresistance

Furthermore, studies have shown that 5amino1mq exerts synergistic effects with exercise intervention on muscle injury repair, further enhancing regeneration efficiency and functional recovery, offering a new direction for exerciseinduced injury rehabilitation research

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However, research conducted over the last four decades has identified a set of complex defense systems against abiotic and biotic factors, involving unique molecular interactions between various compounds and genes commonly found in plant species (De-Bruxelles and Roberts 2001)