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The irradiation of compound 1 (50 M) with white light (3.0 mW cm 2 ) resulted in a quantitative conversion of compound 1 ( t R = 10.7 min) into the oxidized compound 2 ( t R = 10.3 min, 97%) over the course of 10 min, as followed by HPLCmass spectrometry (MS) (Fig
Its initiation is driven by iron overload, oxidative stress, inflammatory cytokines, and disrupted genetic pathways
FBS, foetal bovine serum
