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SSRIs and SNRIs alter serotonin signalling, and when those medications are reduced, the brain must relearn how to produce and regulate serotonin naturally
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The exposures of interest were concentrations of vitamin B12 biomarkers (plasma vitamin B12, MMA, and holoTC), vitamin B12 intake (from foods and/or supplements), intervention with vitamin B12 (any form, duration, or combination with nutrients or drugs), or genetic variants related to B12 metabolism
