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Your tendons and ligaments lose strength and flexibility, making injuries more likely [2] [3]

Similarly, a recent randomized controlled clinical trial evaluating the efficacy of hyaluronic acid enema in preventing acute radiation proctitis in cancer patients (especially those diagnosed with abdominal and pelvic tumors and subsequently requiring radiotherapy) has been completed (NCT06469216)

The apoptosis of retinal ganglion cells (RGCs) is intensified in diabetic retinopathy and the death of the RGCs happens early in diabetic eyes 22

Similarly, caloric restriction has been proposed as a sub-acute anti-glycolytic state that is malaria-protective, but this intervention has pleiotropic physiologic and immunologic effects (Mejia et al., 2015)