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Later studies demonstrated that blocking the local release of norepinephrine inhibits cutaneous vasoconstriction during cold stress without affecting cutaneous vasodilation during heat stress (243) and that presynaptic blockade of cholinergic nerves results in an absence of active cutaneous vasodilation during heat stress (244)
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Ter A also functions as a proteasome inhibitor by reducing chymotrypsin activity and encourages apoptotic cell fatality in tumoral cell lines of the human lung (NCI-H292) [186]
It says theres a concerning lack of published [human] clinical trial data on BPC 157
