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This in turn induces dysfunction of tumor-specific CD8 + T cells and contributes to adaptive resistance to immunotherapies [126,127,128,129,130]

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203 Glutamatergic excitotoxicity Glutamate is the main excitatory neurotransmitter of glutamatergic neurotransmission in the CNS

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Antifungal drugs used to treat a variety of fungal infections can cause Candida die-off

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Data availability The data used to confirm our studys findings are included in the article, and data coding is available from the corresponding author upon reasonable request

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