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Description
Scenario 4: Elderly patient on multiple medications including metformin A 68-year-old with type 2 diabetes takes metformin, a proton pump inhibitor for reflux, and is starting semaglutide for additional glucose control and weight loss
The results that seemed so promising in week one quietly disappear by week six
An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R
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