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M., et al., Epidemiology of Parkinsonism: Incidence, Classification, and Mortality, Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society 16, no

The precise anatomical compartment in which dsNNTTR formation occurs remains to be established

Artesunate inhibited the Notch signaling pathway, decreased Jagged1, NICD, and Hes-1 protein expression, reduced TGF-induced -smooth muscle actin (-SMA) and collagen content in fibroblasts, and inhibited the differentiation of fibroblasts into myofibroblasts (Liu et al., 2017)

These results highlight the potential of these nanoparticles as oral delivery systems for unstable bioactive compounds (100)