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Description
It then binds to intrinsic factor (IF), a glycoprotein secreted by the parietal cells of the gastric mucosa
Activating these receptors triggers a signaling cascade that upregulates hormone-sensitive lipase, which breaks down stored triglycerides into free fatty acids and glycerol essentially mobilizing stored fat for use as energy
The largest published trial (METAOD006/OPTIONS) randomized 502 adults with obesity to AOD-9604 or placebo for 24 weeks alongside a diet and exercise program
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