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They have to bypass the gut entirely
Its a clever, targeted tool but its also one where being honest about realistic expectations matters, especially in a world where GLP-1 medications have raised the bar for what weight loss means
18,19 Besides using LCMS to quantify SAH, detection methods for the SAH are generally indirect and applicable for all SAM-dependent methyltransferases
This regional specificity, combined with the preservation of lean tissue, suggests favorable body composition changes even when total weight loss is moderate
