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Additionally, some CGRP-targeted antibodies can cross BBB to some extent and exert central effects [20, 21]

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97.6% of patients over 40 have a median age of glaucoma diagnosis of 64 years, with the prevalence rising steeply from 0.2% 2.7% in individuals aged 50 59 years to 1.6% 12.8% after age of 80 years (40)
