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MaNagement Specific management guidelines are listed here, with details below: Stop all protein intake Provide hydration with high caloric supplementation Correct biochemical abnormalities Eliminate toxic metabolites Treat precipitating factor(s) Provide cofactor supplementation Prevent associated sequelae 1

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When the mitral valve fails to close and seal completely (mitral valve prolapse being the most common), blood flows backwards into the upper chamber

In dogs, supplementation has been associated with improved exercise performance and recovery in certain contexts, likely by supporting energy availability during activity