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PLD A class of phospholipases that hydrolyze the phosphodiester bond of phosphatidylcholine is phospholipase D, whose action leads to the formation of a signaling molecule, phosphatidic acid, which participates in many fundamental cellular processes such as vesicular transport, exocytosis, autophagy, and consequently regulates cellular metabolism, including contributing to tumorigenesis [52]

Here we report that GSTM1 significantly affects TNF--dependent transcriptional program in astrocytes and modulates neuronal activities and stress during brain inflammation

Subsequent post hoc tests are depicted graphically and show significance between treatments