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In post-surgical or critically ill patients, glutamine may improve nitrogen balance, preserve intestinal integrity, maintain intracellular glutamine levels, and reduce hospital stay (3) (4) (12) (13) (40) , but data on whether it can prevent infections (5) (40) or improve clinical outcomes (57) are mixed and it did not reduce the time to discharge alive from hospital in patients with severe burns (52)
MT-1 and MT-2 are the two isoforms prevalent in the majority of cells and tissues
It can reverse cortisone-induced inhibition of wound healing and restore normal tissue repair signaling without triggering rebound inflammation
Reduced thyroid hormone signaling downregulates tryptophan hydroxylase, impairing serotonin synthesis and contributing to depressive symptoms (71, 72)
