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Description
As a GTPase, Arfs cycle between a GTP and GDP-bound state that is facilitated by GEFs and GAPs [117, 134, 143]
Cytokines in inflammatory disease
Up-regulating SreBP-1 expression raises the activities of fatty acid synthase and acetyl coenzyme A carboxylase, which stimulates the production of fatty acids and cholesterol and causes abnormal lipid buildup in renal tubular cells[41]
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