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Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates

Answers to the questions of how glutathione is transported across the ER membrane and whether any ER glutathione reductase activity exists will increase our understanding of how the cell regulates the glutathione buffer in the ER

This ER stress disrupts LC function, causing cell cycle arrest, apoptosis, and further suppression of testosterone synthesis

GenBank AA305611 EST176607 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end similar to quinolinate phosphoribosyl transferase, nicotinate mononucleotide pyrophosphorylase, mRNA sequence