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Based on these long-term exposure results, kava appeared to be well tolerated in rodents, particularly at a dosage not significantly higher than the human equivalent exposure

[126] In 2000, he assisted local environmental activists to stop Chaffin Light, a real estate developer, and US engineering giant Bechtel from building a large hotel and resort development that, Kennedy argued, threatened coral reefs and public beaches used by local Bahamians, at Clifton Bay, New Providence Island

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Evaluating the protein structural context of affected residues using the three-dimensional structure of recombinant human tetrameric PK has provided a rationale for the observed enzyme deficiency and contributes to a better understanding of the genotype-to-phenotype correlation in PK deficiency