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These treatments employ different mechanisms, with some targeting the TMA/FMO3/TMAO pathway and others working through alternative routes

Herbs showing effects on cytochrome P450s, especially on CYP2C9, CYP1A2, CYP3A4, or CYP2C19, will affect the plasma concentration of warfarin, which may be one of the reasons for herb-warfarin interaction [21]

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