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and lactatate dehydrogenase, LDH) were measured using an auto-analyzer AU-800 (Olympus, Tokyo), and troponin T was assessed by a rapid quantitative assay using the Cardiac Reader (Roche Diagnostics, Mannheim, Germany)

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Consequently, the modification and transformation of NADs and the development of efficient, safe, and targeted delivery systems have become the primary focus of research and development on NADs