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Human explanted hearts The study was approved by the Ethics Committee at the University of Alberta, and all patients provided written informed consents in accordance with the Declaration of Helsinki (2008) of the World Medical Association

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The skin is involved in protecting the body from external factors (e.g., chemicals, pathogens), moisturizing, temperature regulation, and vitamin D synthesis [157,158]

During progression, NOX- and mitochondria-derived H 2 O 2 sustain proliferative signalling by reversibly oxidizing protein tyrosine phosphatases (PTPs), lower thresholds for EMT and promote invasion and immune evasion via redox-tuned cytokine circuits and ECM remodelling (Nigam et al