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The endothelial dysfunction may then cause or aggravate BBB dysfunction which in turn may promote neuroimmune responses, including CNS inflammation, and may also possibly allow access of GPCR to the CNS

After chondrocytes reached 8090% confluency, the cells were dissociated with Trypsin/EDTA (Gibco/Thermo Fisher Scientific) and passaged

10.1111/j.1067-1927.2004.12402.x 21 MaquartF

However, doctors limit the number of these injections that a patient can have in a year to two or three