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Farnesoid X receptor mediates macrophage-intrinsic responses to suppress colitis-induced colon cancer progression

Dey D, Slomka PJ, Leeson P, Comaniciu D, Shrestha S, Sengupta PP, et al

In the previously described multicenter retrospective study of over 500 patients, pruritis (3.3%), flushing (2.0%) and urticaria (1.3%) were the most reported symptoms potentially suggestive of anaphylactoid reaction in the IV NAC cohort, with significantly lower rates in the oral cohort [83]
A potential interpretation could be that the total methylation level of the plant-derived supplements is higher compared to the synthetic preparations
