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showed that in mice, oral treatment of benfotiamine resulted in maximum thiamine concentrations in the liver after 1 h, while maximum concentrations in the blood are reached after 2 h, which led to the conclusion that S-benzoylthiamine from the blood is taken up by the liver and converted to thiamine [4]

89.Kang Y, Yan W, Fang H, Zhang G, Du Y, Wang L, et al

Meanwhile, it has been noted that the efficacy of KD in an array of disorders with distinct pathophysiologies may indicate shared underlying pathologic mechanisms (Kraeuter et al., 2020)

Plant Sci 211:7791 Kolbe A, Oliver SN, Fernie AR, Stitt M, van Dongen JT, Geigenberger P (2006) Combined transcript and metabolite profiling of Arabidopsis leaves reveals fundamental effects of the thiol-disulfide status on plant metabolism