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Immunity 46 , 488503 (2017)
IsoalloLCA, a lithocholic acid (LCA) derivative, enhances peripheral Treg (pTreg) differentiation via FoxP3 upregulation in a TGF- and CNS3-dependent manner through mitochondrial Reactive Oxygen Species (ROS), independent of the Vitamin D Receptor (VDR) (70)
Vitvitsky V, Thomas M, Ghorpade A, Gendelman HE, Benerjee R
Stress & Cortisol Regulation Studies have examined DSIPs ability to modulate the stress response, with research suggesting it may normalise cortisol levels relevant to chronic stress and HPA axis research
