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43 The most important roles of fibroblasts in advanced atherosclerosis involve modulation of the inflammatory response and ECM protein production, and maintenance of the structural integrity of the plaque and balance of MMP production, to promote beneficial tissue remodeling, alongside preventing plaque rupture

Ambroxol (Amb) Ambroxol, an active metabolite of bromhexine, is approved for the treatment of airway diseases in several countries

Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110