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Most importantly, although peptides with the original A 6 -NH 2 or A 5 -dA-NH 2 tails tended to show some off-target proliferation effects in a counterscreen line that is devoid of cellular p53 protein (Ca Ski, Table 2), peptides with the additional Glu residues were largely devoid of proliferation effects in this line (Table 2)

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Ethics declarations Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest