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demonstrated that lactate impairs poly(ADPribose) polymerase 1 (PARP-1) activity by reducing the NAD + /NADH ratio
GSH is utilized to convert H 2 O 2 to H 2 O, accompanied by the production of oxidized glutathione (GSSG), which can be reduced back to GSH through glutathione reductase 1 (GSR1)
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T., Degradation of Misfolded Proteins in Neurodegenerative Diseases: Therapeutic Targets and Strategies, Exp
