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Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress
For this reason, plants are heeled with ferritins and metallothioneins capable of storing iron, copper, and zinc (Halliwell and Gutteridge, 2015)
While ROS play essential signaling roles and help regulate cellular redox status, their over-accumulation disrupts cellular integrity, leading to lipid peroxidation, protein degradation, nucleic acid damage, and ultimately cell death
Keshari P
