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Their method, called Ab Initio Bond Lengths-pK a (AIBL-pK a ) has been shown to be extremely reliable: not only can it be used to predict pK a s of existing or new molecules very accurately, it can also be applied to revise and indeed correct experimental estimates of pK a s when these are affected by measurement errors or inaccuracies

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A randomized phase II study evaluating pyridoxine for the prevention of hand-foot syndrome associated with capecitabine therapy for advanced or metastatic breast cancer