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For example, a healthy, nonepileptic, 16-month-old child ingested a massive overdose (approximately 4 g) of VPA [22]

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The decision-making process should take into account the availability of dialysis equipment and/or staff, the diagnosis and overall condition of the patient, the trend in serum ammonia levels, the response to nitrogen-scavenger therapy and the age and body weight of the patient

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