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NrF2 then serves as a transcription factor for glutathione disulfide, glutathione peroxidase, and glutathione transferases to propagate an antioxidant response, and is suggested as another potential therapeutic target [31]
Additionally, the changes in the function, structure, and chemical processes of fear learning and memory circuits are closely associated with the development of PTSD and also pose considerable challenges for its treatment (Harnett et al., 2020)
Syst Rev (2012) 1:33
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