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After endocytosis of the Hb/Hp complex and erythrocytes, the released heme group primes intraplaque macrophages polarization toward a Mhem phenotype, with consequent activation of the 5-AMP-activated protein kinase (AMPK) and the downstream transcription factor 1 (ATF1) (188, 189)
One strategy is to apply mineral lotion or fluid before leaving the house and reserve sprays for quick touch-ups at the pool or beach

NSBSO was cleaved by GSH and thus experienced a morphological transformation from nanoparticles to nanofibers
