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Genetic deletion of PPAR in macrophages results in decreased FAO and alternative activation while increasing the production of inflammatory cytokines, making them more susceptible to obesity and impairing glucose metabolism (51)

[DOI] [PMC free article] [PubMed] [Google Scholar] Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN
doi: 10.1089/thy.2007.0127 57 LiuHShanZLiCMaoJXieXWangWet al

Environ Microbiol Rep 3, 126
