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The elimination strategy targeting senescent cells thus represents a promising area of research in the context of various pathologies, including cancer, cardiovascular, and neurodegenerative diseases, by targeting the very biological foundation of aging

Moreover, interest in combining systemic immunotherapy with local treatments targeting liver metastases to improve clinical outcomes and overcome drug resistance is increasing

10.1111/j.1742-4658.2005.04596.x 10 BurmeisterC.LersenK.HeinickA.HusseinA.DomagalskiM.WalterR