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FDX1 is a direct target of the ES-Cu 2+ complex, which binds to and inhibits FDX1 function, resulting in mitochondrial dysfunction (Ni et al., 2019)
In a recent study, curcumin, demethoxycurcumin, and bisdemethoxycurcumin significantly attenuated the production of pro-inflammatory cytokines in a MCD diet-induced NAFLD mouse model
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What remains unanswered is whether it is safe for older adults with normal triglyceride concentrations (i.e
