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Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms

Key Takeaway: Avocados are a "superfood" not just for their fats, but because they provide one of the highest dietary concentrations of glutathione, the bodys master antioxidant

One may tell a muscle cell to start repairing while another may reach a sore tendon and call for more blood flow to ease inflammation

Lu R, Osei-Adjei G, Huang X, Zhang Y (2018) Role and regulation of the orphan AphA protein of quorum sensing in pathogenic Vibrios