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PUFAs are the main targets of lipid peroxidation ( Extensive data indicate that ACSL4 and LPCAT3 play important roles in inducing ferroptosis ( Exogenous peroxidation-reactive nonconjugated PUFAs, such as phosphatidylethanolamine containing arachidonic acid (AA) also are considered a key triggering pathway for ferroptosis ( The LOXs family is crucial for initiating enzymatic lipid peroxidation in ferroptosis

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Fermented foods (such as tempeh), nori, spirulina, chlorella algae, and unfortified nutritional yeast cannot be relied upon as adequate or practical sources of B-12.39,40 Vegans must regularly consume reliable sourcesmeaning B-12 fortified foods or B-12 containing supplementsor they could become deficient, as shown in case studies of vegan infants, children, and adults