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References 1.Esser N, Utzschneider KM, Kahn SE (2020) Early beta cell dysfunction vs insulin hypersecretion as the primary event in the pathogenesis of dysglycaemia

In eukaryotic cells, mitochondria, the cytochrome P450 (CYP) enzyme system, peroxisomes, and NADPH oxidases (NOXs) are the main contributors to ROS generation [18,19,20,21,22]

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