enzyme-catalysed conjugations of glutathione with unsaturated compound doi Metabolism S-Conjugates: Multiple Pathways Phase II Detoxification Enzymes |

This selective effect helps maintain the balance of redox states in the intestine, reduces damage to intestinal epithelial cells, protects the intestinal epithelial barrier, and ultimately alleviates intestinal inflammation and symptoms of ulcerative colitis

Furthermore, recent studies have shown that the PKD of JAK2, unlike the other members of the JAK family, exhibits some catalytic activity via autophosphorylation of two critical residues in the JH2SH2 linker region, Ser 523 and Tyr 570 , which play an important role in regulating the activity of the KD (82, 83)

Chioma A

3D, one m6 A modification site with high confidence were uncovered